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SIRTUIN 1
Descriptors Found:
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DeCS
Descriptor
English
:
Sirtuin 1
Descriptor
Spanish
:
Sirtuina 1
Descriptor
Portuguese
:
Sirtuína 1
Synonyms
English
:
Silent Mating Type Information Regulation 2 Homolog 1
Tree Number:
D08.811.277.087.520.200.650.100
D12.776.476.900.100
Definition
English
:
A sirtuin
family
member found primarily in the
CELL NUCLEUS
. It is an NAD-dependent deacetylase with specificity towards
HISTONES
and a variety of
proteins
involved in gene regulation.
History Note
English
:
2010
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
53587
Unique Identifier:
D056564
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS